Activation of Npas1-neurons in the Ventral Pallidum Mediates Stress Susceptibility

2021.10.28 06:11 sburgess86 Activation of Npas1-neurons in the Ventral Pallidum Mediates Stress Susceptibility

Activation of Npas1-neurons in the Ventral Pallidum Mediates Stress Susceptibility submitted by sburgess86 to BiologyPreprints [link] [comments]


2021.10.28 06:11 jkvf1026 I just need to vent & throw myself a pity party for a sec

Yesterday was my 21st birthday & I spent the day at work. I used my time to reflect on my self & I was feeling really happy about everything for once. Like cloud 9, warm & fuzzy, like i dont have health issues including Bipolar 2 happy.
Then I get home & I'm just being myself. I'm naturally loud & bubbly. Every comment my roommate said to me since i got home was degrading & rude & it hard. "Youre too loud, you have too much energy, youre acting so childish" He said it with such irritation like he was revolted to be around me. It's really out of character for him & honestly I was really happy. I lost my insurance but still found a way to stay on my meds & stay healthy, i have addict parents & grew up on air mattresses but now i have my own apartment 3200 miles from where i grew up & then everything he said hit home. I think it's because my famiky used to say those things to me growing up. I've since disowned them.
A bit of background my roommate & I are friends, we were friends first for over a year before he moved in.
Anywho i just walked away from him & went to bed despite wanting to cry on my 21st. Anywho i stayed at my aunts tonight to give us some space and i just can't help but overthink & feel so undesired & not wanted.
Maybe i dont do enough? Like i understand I'm not always able to get up & clean. I run out of spoons or my pain level is too high. It really always comes back to my health, I'm messier because i start things i cant finish, i never cook because i normally cant stand in one place long enough. I lay in bed & sleep for like 16 hours a day so I'm not the most fun.
I always bring it back to my health because it effects my ability to do the dishes or clean out the fridge or clean the bathroom or go out & socialize. Idk guys, I'm just feeling really upset & depressed, first my roommate lashes out on me then as I'm sitting here most of my friends that i call family because i dont have one didnt even text or call. They didnt care. Like i dont know am i that much of a nuisance or a burden? Do they not wanna call because they dont wanna hear what wheel of fortune has for me this week? I honestly dont even talk about my health with anyone, unless it's interfering with something like my pain level. I'll just say "I'm gonna go, my legs hurt" & leave it at that.
I dont really know how to wrap this up or anything, I'm just really distraught and idk how to feel but i want to cry
submitted by jkvf1026 to ChronicIllness [link] [comments]


2021.10.28 06:11 Purple-Quiet3775 CHEAP & LIFETIME SP0TIFY,YOUTUBE TV & PREMIUM,NETFLIXX,NFL,NBA,HB0,PEACOCK,DISNEY+,ADOBE,HULUU,GRAMMARLY,+MORE Streaming & Music & Edu . FOOD R3FUNDS 80% OFF PRICE. FAST SERVICE

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2021.10.28 06:11 Single_Crab_8563 Thinking scientifically quizzes

How did you guys. I personally dropped a few marks, especially in quiz 3 and the final quiz. Frustrated that they won’t reveal the correct answers for the sole reason that the quiz will be reused, after it being my most expensive subject this sem.
submitted by Single_Crab_8563 to unimelb [link] [comments]


2021.10.28 06:11 Acceptable_Ad_7820 To those who wish for a dip, what do you wanna say to them?

To those who wish for a dip, what do you wanna say to them? submitted by Acceptable_Ad_7820 to dogecoin [link] [comments]


2021.10.28 06:11 sburgess86 Social experience dependent plasticity of mouse song selectivity without that of song components

Social experience dependent plasticity of mouse song selectivity without that of song components submitted by sburgess86 to BiologyPreprints [link] [comments]


2021.10.28 06:11 libtin What’s your worst toilet experience?

submitted by libtin to AskReddit [link] [comments]


2021.10.28 06:11 sburgess86 Left angular gyrus disconnection impairs multiplication fact retrieval

Left angular gyrus disconnection impairs multiplication fact retrieval submitted by sburgess86 to BiologyPreprints [link] [comments]


2021.10.28 06:11 nandemotawagoto W / F / L

W / F / L Couldn't resist the neon cow and dalmation! How good was this trade though? People have mostly offered junk for the dragon until this.

https://preview.redd.it/uipp9s0oq5w71.png?width=629&format=png&auto=webp&s=f7abebbbb2d8a06bcaf607cd2f721a483c732049
submitted by nandemotawagoto to AdoptMeTrading [link] [comments]


2021.10.28 06:11 Dear_Feed_9718 alguien conoce un grupo de cum tributes?

submitted by Dear_Feed_9718 to Pajasgrupales2 [link] [comments]


2021.10.28 06:11 sburgess86 Cell region fingerprints enable highly precise single-cell tracking and lineage reconstruction

Cell region fingerprints enable highly precise single-cell tracking and lineage reconstruction submitted by sburgess86 to BiologyPreprints [link] [comments]


2021.10.28 06:11 EMTPirate [WTB] Glock gen 3 frame parts, and polymer sights (OH)

Helping a great guy who is a nogunz get a pistol together on a low budget.
Looking for a Glock 19 Gen 3 lower parts kit with trigger, and polymer Glock sights to finish out his weapon. An optics cover plate would also be great, slide was optics cut no pins (AIM Surplus slide was on sale), but he won't be using one.
$40ish depending on condition and manufacturer.
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2021.10.28 06:11 punkstarpeep Keep on marchin’ on

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2021.10.28 06:11 Straight-Novel-2331 Qui pour échanger nudes de meufs si intéressé venez privé

submitted by Straight-Novel-2331 to SnapNudeTrading [link] [comments]


2021.10.28 06:11 BlazinRedBeard Breakfast “Disco Pizza” fron Nelson Ledges Quarry park. (Waffles, bacon, and a syrup sauce on cheese stuffed biscuit crust)

Breakfast “Disco Pizza” fron Nelson Ledges Quarry park. (Waffles, bacon, and a syrup sauce on cheese stuffed biscuit crust) submitted by BlazinRedBeard to FoodPorn [link] [comments]


2021.10.28 06:11 saragandey Increase power event

#GoTWiCChronicler Lady Acoma
Increase power event is now on in k57!
In this event, you complete the following tasks to earn rewards and rainbow coloured diamonds to redeem on the Honour Day wheel:

  1. Building
  2. Research
  3. Ranking in your kingdom
The Honour Day wheel can grant these rewards if you use the coloured diamonds:
  1. Honour banners
  2. VIP points
  3. Compasses
  4. Gold
I particularly like receiving the compasses which enables me to have a chance at winning some more rewards in Westeros Navigator e.g. lots of diamonds :)
#GOTWIC
submitted by saragandey to GOTWinterIsComing [link] [comments]


2021.10.28 06:11 chowieuk Diners poisoned by sewage at Whitstable oyster festival

Diners poisoned by sewage at Whitstable oyster festival submitted by chowieuk to unitedkingdom [link] [comments]


2021.10.28 06:11 sburgess86 Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes

submitted by sburgess86 to BiologyPreprints [link] [comments]


2021.10.28 06:11 retiredfiend Pain Killer Mask

Is anyone still waiting on their Pain Killer Mask? Or is it just me?
submitted by retiredfiend to joydivizn [link] [comments]


2021.10.28 06:11 yyzworker Case of workers challenging Toronto hospital network's vaccine mandate in court

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2021.10.28 06:11 CritterM72800 Write shorter nonfiction books. Please.

Write shorter nonfiction books. Please. submitted by CritterM72800 to CritterBlog [link] [comments]


2021.10.28 06:11 Kooky-Sort The Limitations with Current Balancing Matrix and suggestions to Improve it

The Current Balance Matrix Has Been Quite Limited for a long time before I show the suggestions let's see the problem
Limitations
Following are the Balancing Matrix Graphs i.e Win Delta and the Top Operator Bans Charts
Y6S3.3
Y6S3.3
As we can see The win Delta tell us the percent global pick rate over all maps and global win rate over all maps of the operators and the ban rates gives us an overall Ban rates over all maps
But we have a lot of limitations such as

  1. What's the Pick rate of the Operator per map?
  2. What's the Win rate per map?
  3. What's Kill per item on the loadout
Why? To have Accurate Data so Balancing Operators doesn't look like we're pressing random Buttons
For Example
Let's take Pick rate per Map Question Presently we only have Data for Total Pick rate of an Operator
How do we know weather the high pick rate is due to That operator having a high pick rate over all Maps or is it just one map? Why do we need the question well if the Operator has a huge Pick rate just because that operator is selected for 1 map that means the operator is situational i.e useful for just that one map which means a nerf or buff isn't necessarily justified for the operator
This Actually Happened when Frost lost her 1.5x because she had a Huge Pick rate with high wins in the Invitational ,But she only being selected for Chalet Map Why? LOTS and LOTS of Windows on Chalet not because Frost is OP , The map gave Frost more Opportunities for Kills and which increase the chances of wins not because Frost has an OP loadout

Y6S2.2 DESIGNER NOTES
The Suggested Improvements
Now this ain't a one stop complete solution to get the most accurate date for operator balance but it's going to make the data more accurate than it's present state All I'm gonna suggest is different Charts some conclusions that can be done using the charts
Since we don't have access to UBI's Database Server we're gonna take the Frost Invitational Situation with the Five Maps Clubhouse Chalet Villa Oregon and Kafe with some assumptions of some random data for the explanations of each of the charts
The Assumption will be Frost has a high Win Rate on Villa Chalet and Clubhouse
The PKW CHART Pick Rate Per Map Graph

Pick rate per Map
The Above Graph gives a lot more info than usual win vs pick chart now we know exactly Frost is used a lot for Chalet than any other Map that means we will need to see what's wrong with the Map
Kills Share Per Map
https://preview.redd.it/0v2gl5lt15w71.png?width=481&format=png&auto=webp&s=13e80c1fc5c444919a44cdab434c4f142b4c043d
This is the Kill Share of each map basically how many Kills out of the Maximum 5 Kills the Operator gets in a match on that Map out of all the times the operator has been picked We can see Frost has Huge Kill share on Maps with more Window Entry Based Like Chalet Clubhouse and Kafe
Win Rate Per Map

PKW Chart
Win Rate per map is the percentages of all won rounds out of all matches of that Map As we can see Frost has higher win rate if she plays on chalet synonymous to her pick and kill rate
This Concludes Our 1st Chart the PKW Chart (Picks Kills Wins Chart) This will gives The Pick Kill and Win rate per Map Helping us to understand weather the Operator is OP or is the Map more Accessible for the Operator
From the above charts we can conclude that :
But we Still have an Issue We don't know the kills percent of gun based kills and Gadget based kills
Let's Start with the
KRX & KRX2 Chart (Kills Expanded and Kills Extra Expanded Chart) as of Now these are the Kill charts

Kills Chart
Now this Graph is going to be Modified with 3 parameters Gun Kills Gadget Kills and Melee Kills i.e
KRX Chart
KRX Chart
Now we get more info on the kills We can now see what part of the loadout of the operator contributes to kills
We can even expand this to individual items of the loadout too
KRX2 Chart

KRX2 Chart
From this Chart we can conclude the majority of kills Frost get are due to her Primary Gun right next to enemies bleeding out on her Frost mats
Please Understand all of this data is made up for the sake of explanation and is not accurate data of frost
The Conclusion
Rainbow six Siege lacks a lot of Statistical Data or their not showing it on the designer notes either way it makes the balance system very inaccurate due to amount of data being hidden by the presently made matrices It would be extremely help to have more In-depth analysis of the Operators
Thank you for reading and Good luck
submitted by Kooky-Sort to Rainbow6 [link] [comments]


2021.10.28 06:11 Mayteras Question about the RC point system in books

How restrictive,or influential,are the points for a certain route?I'm not referring to those who need balanced points.
As a new player,I was playing SOS and I've got 4 courage and 1 caution point.So is it absolutely necessary to be entirely on one point type route(ie,a courage route REQUIRES max available points)or can the player still be on the courage route while having one or two mistakenly chosen caution points?
That was an example of what I wanted to know^
submitted by Mayteras to RomanceClub [link] [comments]


2021.10.28 06:11 PAMediaUK Zoo welcomes birth of endangered black rhino

Zoo welcomes birth of endangered black rhino submitted by PAMediaUK to wholesomenews [link] [comments]


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